Identification of a juvenile-hormone signaling inhibitor via high-throughput screening of a chemical library
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چکیده
منابع مشابه
A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library.
Libraries of compounds are increasingly becoming commercially available for the use of individual academic laboratories. A high-throughput system based on a stably integrated transcriptional reporter was used to screen a library of random compounds to identify agents that conferred robust augmentation of a signal transduction pathway. A novel histone deacetylase (HDAC) inhibitor, termed scripta...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2020
ISSN: 2045-2322
DOI: 10.1038/s41598-020-75386-x